Strategy of discontinuation of PPI

JRCT ID: jRCT1031180383

Registered date:20/03/2019

Basic Information

• Recruitment status: Not Recruiting
• Health condition(s) or Problem(s) studied: Gastroesophageal reflux disease
• Date of first enrollment: 21/08/2019
• Target sample size: 90
• Study type: Interventional
• Intervention(s): Abrupt withdrawal of PPI, and Step-down withdrawal of PPI

Outcome(s)

• Primary Outcome: Withdrawal rate of PPI after 24 weeks
• Secondary Outcome: Withdrawal rate of PPI after 48 weeks

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: GERD patients with long-time use PPI and without symptoms
• Exclude criteria: NSAIDs user, H.pylori positive, and/or severe esophagitis patients

Related Information

• Primary Sponsor: Hojo Mariko