Association between the onset of ICU-acquired weakness and early changes in physical function in critically ill patients

JRCT ID: jRCT1030240589

Registered date:27/12/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Critically ill patients
• Date of first enrollment: 01/11/2024
• Target sample size: 100
• Study type: Observational

Outcome(s)

• Primary Outcome: Presence or absence of ICU-AW onset 14 days after ICU admission
• Secondary Outcome: Limb strength, body composition, quadriceps muscle thickness, cross-sectional area, muscle brightness, FSS-ICU

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

- Patient is expected to be intubated and ventilated for 48 hours or more
- Patient has a life expectancy of 30 days or more at the time of admission

Exclude criteria

-After scheduled surgery
-Persons who have some limitations in their daily lives before hospitalization due to physical or cognitive impairment
-Persons with functional disabilities such as limb loss or motor paralysis
-Persons with a history of acute brain injury, spinal cord injury, neuromuscular disease, or other illnesses that cause muscle weakness
-Persons who are deemed ineligible by a doctor
-Persons with language problems that make communication difficult
-Persons who have been transferred from a general ward
-Persons who have refused to register

Related Information

• Primary Sponsor: Hada Yasushi