PENG & QoR-15: a systematic review and meta-analysis

JRCT ID: jRCT1030240521

Registered date:05/12/2024

Basic Information

• Recruitment status: Suspended
• Health condition(s) or Problem(s) studied: patients who receive hip arthoplasty, including total hip arthroplasty, hemiarthroplasty
• Date of first enrollment: 05/12/2024
• Target sample size: 1000
• Study type: Other
• Intervention(s): PENG block

Outcome(s)

• Primary Outcome: QoR-15, QoR-40 score on POD1 (evaluated within 24 hours from surgery, on postoperative day 1, or on the second day of surgery)

Secondary Outcome

(1) QoR-15 score reported in other time frame: 48 hours or on POD2, etc.
(2) QoR-40 score reported in any time frame: POD1, POD2, etc.
(3) Time to first mobilization: the time from the end of surgery to the first mobilization, ambulation, walk, or getting up from bed
(4) First ambulation distance
(5) First up-and-go test
(6) Quadriceps strength on POD1
(7) Other evaluation tool of recovery or patient-reported outcomes, such as the Hip disability and Osteoarthritis Outcome Score for Joint Replacement (HOOS, JR.), the Patient-Reported Outcomes Measurement Information System (PROMIS)
(8) Patient satisfaction: any satisfaction questionnaire results with perioperative pain management techniques or postoperative analgesia evaluated on a certain scale were included
(9) Postoperative complications reported if possible

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both
• Include criteria: Eligible studies included prospectively registered clinical trials in forms of articles on peer-reviewed journals, letters, or conference abstracts, where (1) adult patients who received any types of hip arthroplasty under either general or spinal anesthesia; (2) patients were allocated to PENG block (including ultrasound-guided, X-ray-guided, CT-guided or traditional landmark-based techniques) as an intervention compared with any other kind of analgesia management other than PENG block for perioperative pain management. No language restrictions were applied. Studies published as Non-English, Chinese, Japanese studies were translated using an online translator.
• Exclude criteria: Exclusion criteria include: (1) studies that had another block as a co-intervention, except for lateral femoral cutaneous nerve (LFCN) block or infiltration using local anesthetics; (2) studies of catheter-based continuous blocks; (3) studies where both intervention and comparison were PENG block; (4) studies with data that could not be used for statistical analysis, or studies with incomplete data, or data that could not be extracted after contacting the original authors; and (5) studies that were duplicate publications, or not prospectively registered.

Related Information

• Primary Sponsor: Jin Zhuan