Assessment of jugular venous valves function during head-down tilt

JRCT ID: jRCT1030240143

Registered date:07/06/2024

Basic Information

• Recruitment status: Pending

Health condition(s) or Problem(s) studied

Healthy adult
cephalad fluid shift symptoms, SANS,space headache, venous thrombosis

• Date of first enrollment: 07/06/2024
• Target sample size: 38
• Study type: Interventional
• Intervention(s): We observe the presence or absence of Internal jugular vein valve reflux using ultrasonography in the supine position and -10 degrees head-down tilt. The duration of -10 degrees head-down tilt is approximately 10 minutes.

Outcome(s)

• Primary Outcome: Presence or absence of jugular vein valve reflux
• Secondary Outcome: Presence or absence of jugular vein valve closure

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: <= 60age old
• Gender: Both

Include criteria

1. Individuals who can be visualized with the right internal jugular vein valve using ultrasound equipment.
2. Individuals who are at least 20 years old and no older than 60 years old at the time of obtaining consent.
3. Individuals who have been assessed through a medical interview and health check-up and have been deemed to be in good health.
4. Individuals who have been provided with a full explanation of the study and have given their free and informed consent to participate in the study.

Exclude criteria

1. Individuals who have declined to participate in the study.
2. Individuals who have cardiovascular diseases (including hypertension and arrhythmias), autonomic nervous system disorders, respiratory diseases, or severe systemic diseases, or who have a history of these conditions (as assessed through medical interview and health check-up).
3. Individuals who have an allergy to ultrasound gel or who have a history of skin rashes or other allergic reactions to ultrasound gel.
4. Individuals who are deemed unsuitable as research subjects by the study investigator.

Related Information

• Primary Sponsor: Kato Tomokazu