Investigation of the dependence of melanopsin-mediated pupillary response on measurement conditions.

JRCT ID: jRCT1030230756

Registered date:29/03/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Healthy subjects
• Date of first enrollment: 29/03/2024
• Target sample size: 30
• Study type: Interventional
• Intervention(s): Measurement of post-illumination pupil response (PIPR): Red or blue LED light is presented for one to several tens of seconds to subjects who have adapted to the dark.

Outcome(s)

• Primary Outcome: Dependence of PIPR measurement results on optical stimulus presentation time and optical system
• Secondary Outcome: Exploling for individual factors (age, gender, pupil sutra, chronotype, mood state, etc.) that contribute to PIPR measurement results and dependence on measurement conditions

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: <= 60age old
• Gender: Both
• Include criteria: 1) Persons who are between 18 and 60 years of age at the time of consent

Exclude criteria

1) Persons with mental illness
2) Those with neurodegenerative diseases
3) Persons with abnormal color vision
4) Persons with a fear of the dark
5) Other subjects deemed inappropriate by the principal investigator.

Related Information

• Primary Sponsor: Kitamura Shingo
• Source(s) of Monetary Support: Japan Society for the Promotion of Science