Sex differences in cerebral blood flow during mild +Gz hypergravity

JRCT ID: jRCT1030230745

Registered date:28/03/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Decreases in cerebral blood flow
• Date of first enrollment: 09/05/2024
• Target sample size: 60
• Study type: Interventional

Intervention(s)

I : 6 min of exposure to mild hypergravity (1.5Gz) generated by the short-arm human human centrifuge
II : 21 min of exposure to mild hypergravity (1.5Gz) generated by the short-arm human human centrifuge

Outcome(s)

• Primary Outcome: cerebral blood flow velocity in the middle cerebal artery, mean arterial pressure at the middle cerebal artery level
• Secondary Outcome: heart rate, mean arterial pressure at heart level, respiratory rate, partial pressure of end-tidal carbon dioxide, peripheral arterial oxygen saturation

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: <= 35age old
• Gender: Both

Include criteria

1. Healthy
2. Regular menstrual cycles (26-38 days)

Exclude criteria

1. Any history of cardiovascular, cranial nerve, respiratory, autonomic nervous disorder, or severe systemic disease
2. Taking hormone drugs, Regular menstrual cycles (26-38 days), and Pregnant

Related Information

• Primary Sponsor: Iwasaki Kenichi