NIPH Clinical Trials Search

JRCT ID: jRCT1030230696

Registered date:13/03/2024

Trends in oxidative and antioxidant indices in cardiopulmonary bypass. A prospective observational study

Basic Information

Recruitment status Complete
Health condition(s) or Problem(s) studiedSubject to cardiac surgery
Date of first enrollment17/01/2022
Target sample size30
Countries of recruitment
Study typeObservational


Primary OutcomeComparison of transition values of oxidative stress and antioxidant capacity in cases of extracorporeal circulation using artificial heart lung in cardiac surgery
Secondary OutcomeAnalysis of differences in oxidative stress and antioxidant capacity values by site of blood collection Correlations with blood gas, biochemistry, and blood counts Relationship to extracorporeal circulatory control values Relationship to inflammatory cytokines

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
Include criteriaA case of extracorporeal circulation using an artificial heart-lung machine in cardiac surgery under general anesthesia
Exclude criteriaPatients who fall under G3a (45 ml/min/1.73 m2) or lower from GFR category (ml/min/1.73 m2) in the CKD Clinical Practice Guidelines 2018 12) issued by the Japanese Society of Nephrology. Patients who undergo other surgical procedures or complex surgeries Patients undergoing emergency surgery When the subject or the subject's family refuses or withdraws consent. Other cases in which the principal investigator determines that the patient is inappropriate.

Related Information


Public contact
Name Tsubasa Yamashiro
Address 4-3, Kozunomori, Narita-shi,Chiba-ken, 286-8686 Japan Chiba Japan 286-8686
Telephone +81-476-20-7701
Affiliation International University of Health and Welfare
Scientific contact
Name Yoshimi Inagaki
Address 852 Hatakeda Narita, Chiba Prefecture 286-0124 JAPAN Chiba Japan 286-0124
Telephone +81-476-35-5600
Affiliation International University of Health and Welfare Narita Hospital