Penicillin oral challenge test for patients with low-risk penicillin allergy.

JRCT ID: jRCT1021230064

Registered date:12/03/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Penicillin allergy
• Date of first enrollment: 12/03/2024
• Target sample size: 10
• Study type: Interventional
• Intervention(s): Take the penicillin antibiotic (amoxicillin) in two steps.

Outcome(s)

Primary Outcome

Presence or absence of an immediate allergic reaction.
If an immediate reaction does not appear, check for a delayed reaction by outpatient or phone after about a week.

Key inclusion & exclusion criteria

• Age minimum: >= 6age old
• Age maximum: <= 15age old
• Gender: Both
• Include criteria: Patients whose age is between 6 and 15 years old and who have been declared by their family members or themselves that they are allergic to penicillin.

Exclude criteria

Patients with delayed language development or intellectual disabilities and have difficulty complaining of allergy symptoms.
Patients who judged that they were at high risk of immediate allergic reaction, Stevens-Johnson syndrome or toxic epidermal necrolysis by risk assessment using the questionnaire.

Related Information

• Primary Sponsor: Shinozaki Toshiyuki