JRCT ID: jRCT1021230051
Registered date:12/01/2024
Safety of dexamethasone suppression test for adrenal masses
Basic Information
Recruitment status | Recruiting |
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Health condition(s) or Problem(s) studied | adrenal mass |
Date of first enrollment | 12/01/2024 |
Target sample size | 40 |
Countries of recruitment | |
Study type | Observational |
Intervention(s) |
Outcome(s)
Primary Outcome | After drawing blood at rest at 23:00 midnight, patients take 1 to 2 dexamethasone 0.5 mg tablets. Fasting resting blood samples will be taken at 6-7 a.m. the next morning, and blood pressure on the morning of dexamethasone administration will be compared with that on the morning of the next day. In addition to adrenocorticotropic hormone and cortisol as originally evaluated in the 1 mg dexamethasone study, blood counts and biochemical tests (blood catecholamine, AST, ALT, ALP, gamma GTP, NT-proBNP, CPK, BUN, Cre, Na, K, Cl) will be taken. |
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Secondary Outcome |
Key inclusion & exclusion criteria
Age minimum | Not applicable |
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Age maximum | Not applicable |
Gender | Both |
Include criteria | Patients admitted to our hospital for the examination of adrenal masses and need to rule out cortisol excess production |
Exclude criteria | Patients on oral steroid therapy. |
Related Information
Primary Sponsor | Murasawa Shingo |
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Secondary Sponsor | |
Source(s) of Monetary Support | |
Secondary ID(s) |
Contact
Public contact | |
Name | Shingo Murasawa |
Address | 5 Zaifu-cho, Hirosaki city, Aomori, 036-8562, Japan Aomori Japan 036-8562 |
Telephone | +81-172-39-5062 |
murashin@hirosaki-u.ac.jp | |
Affiliation | Hirosaki University Graduate School of Medicine |
Scientific contact | |
Name | Shingo Murasawa |
Address | 5 Zaifu-cho, Hirosaki city, Aomori, 036-8562, Japan Aomori Japan 036-8562 |
Telephone | +81-172-39-5062 |
murashin@hirosaki-u.ac.jp | |
Affiliation | Hirosaki University Graduate School of Medicine |