Analgesic effects of ultrasound-guided inferior alveolar nerve block for the removal of impacted mandibular third molar

JRCT ID: jRCT1011220018

Registered date:15/09/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: impacted mandibular third molar
• Date of first enrollment: 15/09/2022
• Target sample size: 104
• Study type: Interventional
• Intervention(s): In the block group, bilateral ultrasound-guided inferior alveolar nerve blocks are performed after the removal of impacted mandibular third molars, and 5 mL each of 0.375% levobupivacaine is administered for a total of 10 mL. In the pracebo group, 5ml each of normal saline is administerd for a total of 10 mL after the same timing and same space.

Outcome(s)

• Primary Outcome: After the block (4, 10, 24 hour), NRS

Secondary Outcome

Pre-/postoperative QoR40J
Complications of nerve block (local anesthetic systemic toxicity, hematoma, local infection)
The number of times rescue analgesics are used in the 24 hours following the block.

Key inclusion & exclusion criteria

• Age minimum: >= 16age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

over 16 years of age
ASA-PS I to II
undergoing the removal of impacted mandibular third molar

• Exclude criteria: Patients who are allergic to the study drug, blood coagulation disorders, chronic opioid use, pregnancy, mental disorders, and other patients who, at the discretion of the physician in charge, are considered inappropriate for this study.

Related Information

• Primary Sponsor: Ishida Yoshiyuki
• Secondary Sponsor: Chaki Tomohiro