POPLAR study

JRCT ID: jRCT1010230018

Registered date:08/07/2023

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Pulmonary hypertension, Interstitial lung disease
• Date of first enrollment: 01/09/2023
• Target sample size: 250
• Study type: Observational

Outcome(s)

• Primary Outcome: Pulmonary vascular resistance
• Secondary Outcome: Data of right heart catheterization, cardiac MRI, respiratory function test, echocardiography, chest CT, urine/blood test, genetic test, biomarker, questionnaire

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1.Male or female who are >=20 years of age at the time of initial PH or ILD diagnosis.
2.With a diagnosis of PAH, ILD-PH, or ILD-no PH at the time of study entry
3.Individuals who voluntarily consent to participate in the study with sufficient understanding after receiving a detailed explanation of it

Exclude criteria

1.Patients who are diagnosed with PH, but classified as group 2, 4, or 5
2.Patients who are classified as group 3 PH without PAH, but have received medication for PAH before baseline
3.Patients who are diagnosed with ILD, the state of which is however expected to change rapidly, including respiratory infection, and drug-induced pneumonia
4.[Prevalent patient only] patients whose first ILD or PH diagnosis was before January 1, 2010.
5.Other individuals who, in the opinion of the sponsor, are not appropriate patients

Related Information

• Primary Sponsor: Tsujino Ichizo
• Secondary Sponsor: Chiang Jason