Association between gastric residual volume and clinical outcomes during post-pyloric enteral nutrition

UMIN ID: UMIN000056973

Registered date:08/02/2025

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Patients who were admitted to the intensive care unit and received the post-pyloric enteral nutrition
• Date of first enrollment: 2025/02/08
• Target sample size: 600
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: 90-day mortality
• Secondary Outcome: 1) ICU length of stay, 2) ICU mortality, 3) 28-day mortality, 4) hospital mortality, 5) ventilator free days, 6) hospital length of stay, 7) Number of days until large GRV occurs, 8) Frequency of large GRV over the duration of the stay, 8) volume of GRV, 9) volume of enteral nutrition, 10) Number of days until the start of post-pyloric nutrition

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Patients who received enteral nutrition via an enterostomy 2) Patients with a history of upper gastrointestinal surgery 3) Patients who were admitted to ICU with diseases that involve digestive tract obstruction, such as intestinal obstruction. 4) Patients for whom gastric residual volume has not been measured

Related Information

• Primary Sponsor: Yokohama City University
• Source(s) of Monetary Support: Self funding