Acute effect characteristics of thigh squeeze hold using a pneumatic cuff on arterial stiffness

UMIN ID: UMIN000056864

Registered date:30/01/2025

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: This study targets healthy adult males and does not focus on any specific disease (no applicable ICD code).
• Date of first enrollment: 2023/07/20
• Target sample size: 10
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Intervention: Compression hold (squeeze hold) applied to the left thigh using a pneumatic cuff Pressure: 100 mmHg, Frequency: 3 sets with a 3-minute rest between sets Posture: Supine position
Intervention: Compression hold (squeeze hold) applied to the left thigh using a pneumatic cuff Pressure: 100 mmHg, Frequency: 5 sets with a 3-minute rest between sets Posture: Supine position
Intervention: Compression hold (squeeze hold) applied to the left thigh using a pneumatic cuff Pressure: 200 mmHg, Frequency: 3 sets with a 3-minute rest between sets Posture: Supine position

Outcome(s)

• Primary Outcome: Main Outcome: Cardio-Ankle Vascular Index (CAVI) Measurement Timing: Before the intervention (after 10 minutes of supine rest) and 10 minutes after the completion of the final intervention. The mean coefficient of variation for CAVI measurements was reported to be 3.8% by Shirai et al. (2006), indicating high reliability.
• Secondary Outcome: heart rate and blood pressure Measurement Timing: Before the intervention (after 10 minutes of supine rest) and 10 minutes after the completion of the final intervention.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 45years-old
• Gender: Male
• Exclude criteria: Individuals with exercise habits and those with peripheral arterial, coronary artery, cerebrovascular, or lower limb orthopedic diseases

Related Information

• Primary Sponsor: Tokushima Kensei Hospital
• Source(s) of Monetary Support: none