Test of the Improvement in Bone Density and Secondary Effects of Hydrogen Coral Powder Supplements in Pre-Osteoporosis Cases

UMIN ID: UMIN000056776

Registered date:22/01/2025

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Women aged 40 to 75 with pre-osteoporosis
• Date of first enrollment: 2024/10/01
• Target sample size: 10
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): Take five capsules of hydrogen coral powder supplements daily, divided into two doses in the morning and evening

Outcome(s)

• Primary Outcome: Bone density (femur and lumbar spine)
• Secondary Outcome: Blood tests, body composition measurements (height, weight, muscle mass, etc.), and skin frailty-related tests

Key inclusion & exclusion criteria

• Age minimum: 40years-old
• Age maximum: 75years-old
• Gender: Female
• Exclude criteria: If the attending physician determines that participation in the trial is inappropriate. History of fractures caused by osteoporosis. Severe diabetes, hypertension, etc. Presence of thyroid disease. Currently taking calcium channel blockers. Due to hypercalcemia as a side effect of vitamin D, blood vitamin D levels and blood calcium levels should be measured and considered.

Related Information

• Primary Sponsor: Meguro Komazawa Lihabilitation Orthopedic Clinic
• Source(s) of Monetary Support: First Co.,Ltd.