UMIN ID: UMIN000056469
Registered date:16/12/2024
Develpoment of xerostomia treatment targeting minor salivary glands -Occlusal stimulation and minor gland sarivary secretion-
Basic Information
| Recruitment status | Pending |
|---|---|
| Health condition(s) or Problem(s) studied | Xerostomia |
| Date of first enrollment | 2024/12/24 |
| Target sample size | 18 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Bite the splint disk with a thickness of about 1mm with upper and lower teeth. Dental local infiltration anesthesia into the gingiva (Oral injection dental cartridge) |
Outcome(s)
| Primary Outcome | Minor salivary glands secretion |
|---|---|
| Secondary Outcome | Bite force, Whole salivary flow rate |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 55years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Adults who are allergic to dental local anesthetics. Adults with hypertension, arteriosclerosis, heart failure, hyperthyroidism, and diabetes. Adults who are unable to make self-judgments due to dementia, etc. Adults who are pregnant, breastfeeding, or wish to become pregnant during the research period. Others who are judged be a dentist to be inappropriate for study participation. |
Related Information
| Primary Sponsor | Tohoku University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Tohoku University |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masahiro Iikubo |
| Address | 4-1 Seiryo-machi Aoba-ku Sendai Japan 980-8575 |
| Telephone | 022-717-8930 |
| masahiro.iikubo.c6@tohoku.ac.jp | |
| Affiliation | Tohoku University Division of Dental Informatic Radiology |
| scientific contact | |
| Name | Shizuko Satoh |
| Address | 4-1 Seiryo-machi Aoba-ku Sendai Japan |
| Telephone | 022-717-8434 |
| shizuko.sato.e7@tohoku.ac.jp | |
| Affiliation | Tohoku University Hospital Division of Comprehensive Dentistry |