Study on single oral intake of processed garlic food in healthy subjects

UMIN ID: UMIN000056177

Registered date:18/11/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Healthy Adults
• Date of first enrollment: 2024/11/19
• Target sample size: 40
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

In this study, the participants consume a specified standard diet for dinner on the day before the study and breakfast on the day of the study. On the day of the study, a single tablet of a supplement containing garlic-derived ingredients is taken with mineral water, and blood samples are taken 0, 0.5, 1, and 2 hours after intake.
In this study, the participants consume a specified standard diet for dinner on the day before the study and breakfast on the day of the study. On the day of the study, a single tablet of placebo food is taken with mineral water, and blood samples are taken 0, 0.5, 1, and 2 hours after intake.

Outcome(s)

• Primary Outcome: Plasma NAD+ synthesis-related component concentrations, and plasma NAD+ synthesis-related activity
• Secondary Outcome: Plasma garlic processed food-derived component concentrations Blood Biochemistry Tests Blood pressure Pulse rate

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 49years-old
• Gender: Male and Female
• Exclude criteria: 1.Persons with severe gastrointestinal, hepatic, renal, circulatory, hematological, endocrine, or malignant neoplasm, or suspected or existing malignant neoplasm 2.Persons with a BMI of 30 or higher 3.Women who are menstruating or menopausal 4.Persons are allergic to standard foods and test foods 5.Persons who usually take medicine, specified health food, healthy food and supplements containing NAD intermediate metabolites (complex vitamins, nicotinamide mononucleotide (NMN)) 6.Persons who have participated in other tests within the first month before the start of the test, or those who intend to participate in another exam after consenting to this exam 7.Persons who were judged as inappropriate for study participants by the principal investigator 8.Persons who are pregnant, planning or hoping to be pregnant during the study period, breastfeeding

Related Information

• Primary Sponsor: Healthcare Systems Co., Ltd.
• Secondary Sponsor: Institute for Research on Productive Aging; IRPA
• Source(s) of Monetary Support: Wakunaga Pharmaceutical Co., Ltd.