An observational study on the association between oral microflora and ventilator-associated pneumonia in Vietnam

UMIN ID: UMIN000055978

Registered date:29/10/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: ventilator-associated pneumonia
• Date of first enrollment: 2024/11/25
• Target sample size: 30
• Countries of recruitment: Japan,Asia(except Japan)
• Study type: Observational

Outcome(s)

• Primary Outcome: Differences in oral flora in intubated patients with and without VAP using real-time PCR: during the first 7 days from case enrollment
• Secondary Outcome: Aassociation of bacterial flora in sputum and oral specimens in patients with VAP

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Patients with pneumonia prior to intubation 2) Patients who have been extubated/left ICU/deceased within 48 hours of intubation 3) Patients with trauma to the head, neck, or face 4) Patients whose oral cavity is contaminated with blood 5) Patients with trauma or signs of infection in the oral cavity prior to intubation 6) Those who are judged as unsuitable by the principal investigator or the project leader

Related Information

• Primary Sponsor: National Center for Global Health and Medicine
• Source(s) of Monetary Support: SUNSTAR INC.