The Relationship Between Social Isolation and Appetite: A Magnetoencephalography (MEG) Study on Neural Mechanisms

UMIN ID: UMIN000055861

Registered date:17/11/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Social Isolation
• Date of first enrollment: 2024/12/31
• Target sample size: 50
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): Presentation of food and non-food images

Outcome(s)

• Primary Outcome: Magnetoencephalography (MEG) data, social isolation-related indicators (Japanese version of the Lubben Social Network Scale short version (LSNS-6), Japanese version of the UCLA Loneliness Scale (Version 3): UCLA Loneliness Scale Version 3), and the Visual Analogue Scale (VAS).
• Secondary Outcome: Survey on daily appetite and eating behavior (Three Factor Eating Questionnaire: TFEQ), Connor-Davidson Resilience Scale (CD-RISC), Japanese version of the Hospital Anxiety and Depression Scale (HAD), Positive Affect Negative Affect Schedule (PANAS), Pittsburgh Sleep Quality Index (PSQI), and Japanese version of the Salzburg Stress Eating Scale (SSES-J).

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 100years-old
• Gender: Male and Female
• Exclude criteria: 1. Individuals with current or past neurological, visual, or psychiatric disorders, or other severe diseases 2. Individuals receiving medication for any condition 3. Individuals with contraindications for MRI 4. Smokers 5. Individuals with metal present in their body (especially in the head and neck region), which could cause metal-related noise interference in magnetoencephalography 6. Individuals in peri-menopause or post-menopause, based on self-reported last menstrual cycle 7. Individuals with a history of severe medical or neurological disorders, or those with a current or past history of psychiatric disorders 8. Individuals with comorbidities such as cardiovascular disease or diabetes, or a history of weight-loss surgery or abdominal surgery 9. Individuals using medications that may affect the central nervous system, regularly taking painkillers, or those who are pregnant or breastfeeding 10. Individuals engaging in extreme vigorous exercise (continuous exercise for more than 8 hours per week)

Related Information

• Primary Sponsor: Osaka Metropolitan University
• Source(s) of Monetary Support: Osaka Metropolitan University