UMIN ID: UMIN000055838
Registered date:03/01/2025
A retrospective clinical study on the prognosis and incidence of fractures between calcimimetics users and non-users in dialysis patients with achievement of PTH management target value
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Patients with end-stage kidney disease undergoing hemodialysis and online hemodiafiltration |
| Date of first enrollment | 2024/11/01 |
| Target sample size | 500 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | 2-year all-cause mortality |
|---|---|
| Secondary Outcome | 2-year incidence of fractures |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1 Use of dialyzers with beta2-microgloburln clearance below 70 mL/min 2 Missing data for covariates at study entry 3 Dialysis conditionssuch as dialysis method and membrane material between April 1, 2017 and June 30, 2017, which are different from those as of July 1, 2017 4 Blood purification methods other than hemodialysis and online hemodiafiltration 5 Dialysis frequency below 3 sessions per week or dialysis time below 3 hour per session 6 Pregnant or lactating patients 7 Patients with below 60pg/mL or over PTH 241pg/mL |
Related Information
| Primary Sponsor | Others |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Nothing |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Manabu Tashiro |
| Address | 6-1 Kitasako ichiban-cho, Tokushima-shi, Tokushima,Japan Japan 7700011 |
| Telephone | 0886310110 |
| m.tashiro@khg.or.jp | |
| Affiliation | Social medical corporation Kawashimakai Kawashima Hospital Department of Nephrology |
| scientific contact | |
| Name | Kazuyoshi Okada |
| Address | 6-1 Kitasako ichiban-cho, Tokushima-shi, Tokushima, J Japan |
| Telephone | 088-631-0110 |
| kokada@minos.ocn.ne.jp | |
| Affiliation | Social medical corporation Kawashimakai Kawashima Hospital Blood purification management center |