Impact of inhaled nitric oxide therapy in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation combined with Impella

UMIN ID: UMIN000055585

Registered date:22/09/2024

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: consecutive patients supported with ECPELLA for CS due to acute myocardial infarction (AMI) and non-compensated heart failure
• Date of first enrollment: 2024/08/29
• Target sample size: 50
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: The primary endpoint was the comparison of 30-day all-cause mortality between patients with iNO and without iNO.
• Secondary Outcome: The secondary endpoints were comparisons of the VA-ECMO withdrawal rate and duration between patients with and without iNO therapy, as well as changes in hemodynamic- and MCS-related parameters after the initiation of iNO therapy.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: Under 20 years of age

Related Information

• Primary Sponsor: Kindai University
• Source(s) of Monetary Support: Kindai University