UMIN ID: UMIN000055550
Registered date:24/09/2024
Nab-paclitaxel or paclitaxel for relapsed small cell lung cancer: a systematic review and meta-analysis
Basic Information
| Recruitment status | Pending |
|---|---|
| Health condition(s) or Problem(s) studied | Relapsed small cell lung cancer |
| Date of first enrollment | 2024/09/24 |
| Target sample size | |
| Countries of recruitment | Japan |
| Study type | Others,meta-analysis etc |
| Intervention(s) |
Outcome(s)
| Primary Outcome | The primary endpoint is to evaluate the efficacy and the safety of nab-paclitaxel or paclitaxel monotherapy as 2nd line or later treatment for extensive stage SCLC. 3-month progression survival rate, 6-month overall survival rate, objective response rate and disease control rate will be evaluated. |
|---|---|
| Secondary Outcome | As the additional analysis, the frequency of adverse events of nab-paclitaxel or paclitaxel such as the occurrence rate of neuropathy, drug-induced pneumonia, neutropenia, anemia, thrombocytopenia and any G5 adverse events. |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | (1) Systematic review or meta-analysis papers. (2) Case series with less than 5 patients (3) Patients who used the regimen of carboplatin, nab-paclitaxel, or carboplatin, paclitaxel. (4) Clinical studies which do not evaluate neither the efficacy nor the safety of nab-paclitaxel or paclitaxel. (5) Papers not written in English. (6) Conference abstracts |
Related Information
| Primary Sponsor | Yokohama City University Graduate School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Nothing |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Sousuke Kubo |
| Address | 3-9 Kanazawa-ku, Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa, Japan Japan 2360004 |
| Telephone | 0457872800 |
| kubo.sos.ii@yokohama-cu.ac.jp | |
| Affiliation | Yokohama City University Graduate School of Medicine Department of Pulmonology |
| scientific contact | |
| Name | Sousuke Kubo |
| Address | 3-9 Kanazawa-ku, Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa, Japan Japan |
| Telephone | 0457872800 |
| kubo.sos.ii@yokohama-cu.ac.jp | |
| Affiliation | Yokohama City University Graduate School of Medicine Department of Pulmonology |