A comparative study of the discontinuation rate of Intravenous patient-controlled analgesia used after posterior spinal fusion surgery with intraoperative ondansetron administration. 1

UMIN ID: UMIN000054614

Registered date:10/06/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: posterior spinal fusion surgery
• Date of first enrollment: 2024/04/01
• Target sample size: 50
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Anesthesia is administered by inhalation with sevoflurane and remifentanil. Fentanyl 9 mcg/kg and acetaminophen 15 mg/kg are administered as intraoperative analgesics. Transvenous patient-controlled analgesia is used for a total of 60 ml of fentanyl, saline, and 5 mg of droperidol to achieve 0.5 mcg/kg/h of fentanyl when used at 2 ml/h. During surgery, 4 mg of ondansetron and 1.25 mg of droperidol are administered.
Anesthesia is administered by inhalation with sevoflurane and remifentanil. Fentanyl 9 mcg/kg and acetaminophen 15 mg/kg are administered as intraoperative analgesics. Transvenous patient-controlled analgesia is used for a total of 60 ml of fentanyl, saline, and 5 mg of droperidol to achieve 0.5 mcg/kg/h of fentanyl when used at 2 ml/h. During surgery, 1.25 mg of droperidol are administered.

Outcome(s)

• Primary Outcome: the discontinuation rate of transvenous patient-controlled analgesia

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1. Asthma 2. Long QT syndrome 3. Patients who did not give consent

Related Information

• Primary Sponsor: Nagasaki rosai hospital, Anesthesiology, Yuki Soejima
• Source(s) of Monetary Support: Nagasaki rosai hospital
• Secondary ID(s): 0513