Study on the change of Na excretion by different time of urine collection and the effect of salt intake on blood pressure while sleeping

UMIN ID: UMIN000054540

Registered date:01/06/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Adult
• Date of first enrollment: 2024/06/01
• Target sample size: 80
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Low salt diet - breakfast high salt diet
Breakfast high-salt diet - low-salt diet
Low salt diet - high salt diet for dinner
Dinner High-salt diet - Low-salt diet

Outcome(s)

• Primary Outcome: Spot urine sodium (Na) excretion, potassium (K) excretion and creatinine (Cre) excretion. 24-hour urine Na excretion, K excretion and Cre excretion. Preprandial and nocturnal blood pressure.

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 30years-old
• Gender: Male and Female
• Exclude criteria: No serious liver disease, renal disease, autoimmune disease, diabetes, dyslipidemia, metabolic syndrome, thyroid disease, or other diseases requiring medical treatment in the past or present medical history, and no dietary supplements.

Related Information

• Primary Sponsor: Kobe Gakuin University
• Source(s) of Monetary Support: Kobe Gakuin University