Multicenter retrospective study of the Efficacy of Adjuvant Immunotherapy after Radical therapy (Surgery or Radiotherapy) for Urothelial Carcinoma (Michinoku Study 1015)

UMIN ID: UMIN000054315

Registered date:07/05/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: Bladder cancer
• Date of first enrollment: 2024/05/07
• Target sample size: 2500
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: The efficacy (progression-free survival, cancer-specific survival, and overall survival) of immunotherapy after local treatment for urothelial carcinoma (bladder cancer, pyelonephritis) will be compared with that of no treatment or chemotherapy after local treatment. Overall analysis as well as analysis by cancer site and intervention method will be performed.

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 100years-old
• Gender: Male and Female
• Exclude criteria: Patients with urothelial carcinoma (bladder cancer, cancer of the renal pelvis and ureter) for which treatment intervention is unknown, patients for whom important outcomes (recurrence, death, date of last confirmed survival, etc.) are unknown, patients who cannot be followed for observation periods of less than 3 months, etc., and patients who have indicated refusal to participate.

Related Information

• Primary Sponsor: Hirosaki University
• Source(s) of Monetary Support: None