UMIN ID: UMIN000054257
Registered date:25/04/2024
Comparison of dexmedetomidine and magnesium sulphate in laparoscopic cholecystectomy
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Symptomatic cholelithiasis |
| Date of first enrollment | 2014/01/08 |
| Target sample size | 45 |
| Countries of recruitment | Asia(except Japan) |
| Study type | Interventional |
| Intervention(s) | Patients were given 100ml NS 0.9% IV (group NS, n=15) over a period of 10 minutes in double blinded manner after induction of anaesthesia but before creation of pneumoperitoneum Patients were given Dexmedetomidine 1microgm/kg in 100ml NS (group DX, n=15) in double blinded manner after induction of anaesthesia but before creation of pneumoperitoneum Patients were given or magnesium sulphate 50mg/kg in 100 ml NS (group MG, n=15) in double blinded manner after induction of anaesthesia but before creation of pneumoperitoneum |
Outcome(s)
| Primary Outcome | To study and compare the effects of intravenous single dose dexmedetomidine and magnesium sulphate on haemodynamic parameters in patients undergoing elective laparoscopic cholecystectomy under general anaesthesia |
|---|---|
| Secondary Outcome | ioflurane concentration, pain, post operative nausea and vomiting, sedation |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 60years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients with history of cardiovascular disease, endocrine disease like uncontrolled diabetes mellitus, thyroid disorder, compromised renal, hepatic, neuronal functions, pregnant or lactating females or any patient taking drugs affecting cardiovascular parameters . Conversion of laparoscopic to open cholecystectomy, excessive internal bleeding leading to hypotension or requiring blood transfusion or duration of pneumoperitoneum more than 2 hours |
Related Information
| Primary Sponsor | University College of Medical Sciences AND GTB Hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | University College of Medical Sciences AND GTB Hospital |
| Secondary ID(s) |
Contact
| public contact | |
| Name | ANKITA KAASAT |
| Address | NH-8, Rajsamand, Rajasthan(313202) , INDIA Japan 313202 |
| Telephone | 6361854732 |
| ankitakaasat@gmail.com | |
| Affiliation | Ananta Institute of Medical Sciences and Research Centre DEPARTMENT OF ANAESTHESIA AND CRITICAL CARE |
| scientific contact | |
| Name | ANKITA KAASAT |
| Address | NH-8, Rajsamand, Rajasthan(313202) , INDIA Japan |
| Telephone | 6361854732 |
| ankitakaasat@gmail.com | |
| Affiliation | Ananta Institute of Medical Sciences and Research Centre DEPARTMENT OF ANAESTHESIA AND CRITICAL CARE |