Effects of combined neuromuscular electrical stimulation and aerobic exercise on exercise tolerance and microcirculation in patients with chronic heart failure.

UMIN ID: UMIN000054255

Registered date:30/04/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: heart failure
• Date of first enrollment: 2024/04/30
• Target sample size: 20
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Treatment group Wear a power suit equipped with electrodes arranged to correspond to 14 muscles in total of 7 parts:abdominal rectus muscle,abdominal oblique muscle,biceps,triceps,gluteus maximus muscle,quadriceps,and hamstring. Perform electrical stimulation at a frequency of 4Hz through electrodes. The stimulation intensity is the maximum strength that can be tolerated. Wear a power suits and do 20 sessions of aerobic exercise for 1 hour(30 minutes of gymnastics and 30 minutes of bicycle ergometer)once with the intensity of AT.
sham group As with the treatment group,perform 20 sessions of 1 hour of aerobic execise(30 minutes of gymnastics and 30 minutes of bicycle ergometer)at the intensity of AT while wearing a power suit. Electrical stimulation shall not be flowed.

Outcome(s)

• Primary Outcome: 402(peak),402(AT)after 20 sessions from baseline
• Secondary Outcome: Body composition Knee extenshion muscle strength FMD The amount of change in walking distance for 6 minutes Blood sugar level Lactic acid value

Key inclusion & exclusion criteria

• Age minimum: 40years-old
• Age maximum: 85years-old
• Gender: Male and Female
• Exclude criteria: Patients who fall under the contraindications of NMES use when inserting a pacemaker(skeletal muscle electrical stimulation guidelines) Patienta who fall under the contraindications of exercise therapy described in the mental rehaling guidelines Patients with limb defects Patients who have difficulty walking independently Patients who have difficulty implementing NMES due to skin diseases,wounds,and itching patients whose doctor in charge determined that it was inappropriate to participate in the research

Related Information

• Primary Sponsor: Dokkyo Medical University Nikko Medical Center
• Source(s) of Monetary Support: Ministry of Education,Culture,Sports,Science and Technology