Evaluating significance of Geriatric Assessments, a multicenter Prospective Observational Study in real World diffuse large B-cell lymphoma patients of Elderly.

UMIN ID: UMIN000054212

Registered date:21/04/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Diffuse large B-cell lymphoma
• Date of first enrollment: 2024/04/25
• Target sample size: 500
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: Evaluation of physical and physiological function decline in elderly DLBCL patients using a geriatric assessment and construction of a frailty scale.
• Secondary Outcome: Understanding the treatment outcomes in elderly DLBCL patients. Evaluation of initial treatment conditions using the newly constructed frailty scale derived from geriatric assessments. Assessment of the relationship between the newly constructed frailty scale from geriatric assessments and clinical outcomes. Evaluation of the relationship between treatment intensity, clinical outcomes, and the newly constructed frailty scale from geriatric assessments. Evaluation of the efficacy and safety of initial treatment regimens in elderly DLBCL patients. Understanding geriatric assessments.

Key inclusion & exclusion criteria

• Age minimum: 70years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: (1) Patients who are judged by the principal investigator or sub-investigator to be inappropriate to participate in this study.

Related Information

• Primary Sponsor: G-POWER Study Group
• Source(s) of Monetary Support: Chugai Pharmaceutical Co., Ltd.