UMIN ID: UMIN000054198
Registered date:21/04/2024
Diagnostic Capability for Colitis Due to Immune-Related Adverse Events (irAEs) with a Focus on Intestinal T Cells
Basic Information
| Recruitment status | Recruiting |
|---|---|
| Health condition(s) or Problem(s) studied | Gastrointestinal disorders associated with irAE |
| Date of first enrollment | 2024/04/22 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | We isolate lymphocytes from gastrointestinal mucosal biopsy samples of patients undergoing immune checkpoint inhibitor therapy and perform flow cytometry to analyze the composition of lymphocyte fractions. We explore whether the diagnosis of irAE gastrointestinal damage can be based on the proportions of specific T cell subsets. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 90years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Women who are pregnant or may be pregnant |
Related Information
| Primary Sponsor | Okayama University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Self funding |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masaya Iwamuro |
| Address | 2-5-1 Shikata-cho, Kita-ku Japan 700-8558 |
| Telephone | 0862357218 |
| iwamuromasaya@yahoo.co.jp | |
| Affiliation | Okayama University Hospital Department of Gastroenterology |
| scientific contact | |
| Name | Masaya Iwamuro |
| Address | 2-5-1 Shikata-cho, Kita-ku, Okayama Japan |
| Telephone | 0862357218 |
| iwamuromasaya@yahoo.co.jp | |
| Affiliation | Okayama University Hospital Department of Gastroenterology |