UMIN ID: UMIN000054149
Registered date:16/04/2024
Milrinone versus dobutamine as supportive agent for right ventricular dysfunction after cardiopulmonary bypass: a prospective randomized comparative study
Basic Information
| Recruitment status | Pending |
|---|---|
| Health condition(s) or Problem(s) studied | active |
| Date of first enrollment | 2024/04/15 |
| Target sample size | 54 |
| Countries of recruitment | Africa |
| Study type | Interventional |
| Intervention(s) | Milrinone group (M group) will include patients who will be subjected to milrinone a loading dose of milrinone acetate 50 mic/kg over 10 minutes followed by 0.3-0.8 mic/kg/min. infusion. Dobutamine group (D group) will include patients who will be subjected to 2-10 mic/kg/min intravenous infusion. |
Outcome(s)
| Primary Outcome | Transesophageal echocardiography indices of right ventricular function (TAPSE, RV FAC, RV basal diameter and S of tissue doppler). |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 70years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Emergency surgery Prior intake of inotropic support. Severe hepatic, renal impairment. Patients for pulmonary thromboendarterectomy, Contraindication for use of TEE |
Related Information
| Primary Sponsor | Mansoura university hospitals |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Mansoura university hospitals |
| Secondary ID(s) |
Contact
| public contact | |
| Name | mohammed adel hegazy |
| Address | Anesthesia and ICU faculty of Medicine Mansoura University Japan 35511 |
| Telephone | 0020502205178 |
| dr_mhegazy7000@mans.edu.eg | |
| Affiliation | Mansoura university hospital anesthesia and surgical intensive care department |
| scientific contact | |
| Name | Mohammed Adel Hegazy |
| Address | Anesthesia and ICU faculty of Medicine Mansoura University Japan |
| Telephone | 0020502205178 |
| dr_mhegazy7000@mans.edu.eg | |
| Affiliation | Mansoura university anesthesia and surgical intensive care department |