Effects of season, physical activity, and water consumption on water turnover: N-of-1 crossover intervention trial

UMIN ID: UMIN000054110

Registered date:10/04/2024

Basic Information

• Recruitment status: Pending
• Health condition(s) or Problem(s) studied: n/a
• Date of first enrollment: 2024/04/29
• Target sample size: 1
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): The intervention period lasts 56 weeks, with 4 intervention trials conducted across 7 cycles. Each cycle includes 4 intervention trials of 10 days each, with a 3-day washout period between trials. Control (10 days x 7/year),increased water consumption (+1500 ml/day, 10 days x 7/year), increased physical activity (walking +9.4 km/day, 10 days x 7/year), increased water + increased physical activity (water consumption +1500 ml/day, walking +9.4 km/day, 10 days x 7/year)

Outcome(s)

• Primary Outcome: water turnover
• Secondary Outcome: 24 h urine volume, urinary biomarkers, blood biomarkers, defecation status, dietary intake, PWV

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 30years-old
• Gender: Female
• Exclude criteria: Patients with serious illnesses such as cancer, myocardial infarction, stroke, etc.

Related Information

• Primary Sponsor: Waseda University
• Secondary Sponsor: National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition
• Source(s) of Monetary Support: Japan Science and Technology Agency Charitable Trust