CT-Angiography-Derived Plaque Characteristics and Cardiovascular Events in Deferral Patients by Invasive Fractional Flow Reserve

UMIN ID: UMIN000054067

Registered date:04/04/2024

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: chronic coronary syndromes (CCS)
• Date of first enrollment: 2014/04/01
• Target sample size: 400
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: Cardiac events were defined as a composite of cardiac death, non-fatal acute coronary syndrome (ACS), and ischemia-driven revascularization for patient-based analysis. Cardiac events were redefined as lesion-level ACS and lesion-level ischemia-driven revascularization.
• Secondary Outcome: Secondary endpoints are the individual components of the primary endpoints.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: The exclusion criteria are 1) patients with a history of coronary bypass grafting (CABG) because CABG changed local coronary flow dynamics, 2) patients with left-main disease, and 3) patients with FFR in stented vessels due to inability to estimate plaque morphology in the stented lesion by CTA.

Related Information

• Primary Sponsor: Fujita Health University School of Medicine
• Source(s) of Monetary Support: Fujita Health University School of Medicine