Investigating the risk of ventilator-induced lung injury in patients with acute respiratory distress syndrome using lung stress mapping: multicenter prospective observational study

UMIN ID: UMIN000053876

Registered date:15/03/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: ARDS
• Date of first enrollment: 2023/12/11
• Target sample size: 100
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: To clarify Lung stress mapping and to determine the association between the amount of high Lung stress areas in the lungs and ventilator-free days.

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Patients with esophageal diseases (post-esophageal surgery, active bleeding, etc.) that make esophageal intra-esophageal pressure measurement impossible. 2) Patients with do-not-resuscitate (DNR) 3) Patients on home ventilator management 4) Patients with a ventricular assist device (VAD) or a venous-arterial extracorporeal membrane ventricular pump (VA-ECMO) for heart failure 5) Patients with a history of neuromuscular disease 6) Pregnant women

Related Information

• Primary Sponsor: Osaka University Graduate School of Medicine
• Source(s) of Monetary Support: Japan Science and Technology Agency