Effect of eating speed on the digestion and absorption rate

UMIN ID: UMIN000053871

Registered date:15/03/2024

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Healthy adult males
• Date of first enrollment: 2023/12/07
• Target sample size: 16
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Rapid eating trial (60% of regular eating duration). Intervention periods was 8 days (4 days in free living condition and 4 days in laboratory conditions).
Slow eating trial (200% of regular eating duration). Intervention periods was 8 days (4 days in free living condition and 4 days in laboratory conditions).

Outcome(s)

• Primary Outcome: Energy loss from stool and urine. In the eating speed intervention, each trial will be conducted for 8 days.
• Secondary Outcome: Oral and gut microbiota and metabolites, transit time

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 39years-old
• Gender: Male
• Exclude criteria: - Under 18 years old - Over 40 years old - Females - Those who habitually do not defecate more than once a day - Patients with regular medication (diabetes treatment, alpha-blockers, beta-blockers, and other medications that affect metabolism) - Those who have diseases that affect metabolism (diabetes, thyroid disorders) - Those with a diagnosis of or history of mental illness - Patients with pacemakers or other implantable medical devices - Those with serious cardiovascular disease - Those with acute stage cancer - Those who have dental and oral problems - Those who have a history of gastrointestinal surgery (mainly esophagus, stomach, duodenum, small intestine, colon, and liver. However, appendicectomy is acceptable) - Those who have gastrointestinal disease - Those with knee or back problems that interfere with daily life - Those who have extremely irregular eating habits - Those who have exercise habits (average 60 minutes/day or more) - Those who are currently participating in, or intend to participate in, a study involving the ingestion of other foods, the taking of drugs, or the application of cosmetics or drugs, etc. - Those with drinking and smoking habits and cannot be controlled during the study period

Related Information

• Primary Sponsor: National Institutes of Biomedical Innovation, Health and Nutrition
• Source(s) of Monetary Support: Grants-in-Aid for Scientific Research