UMIN ID: UMIN000049191
Registered date:11/10/2022
Evaluation of the Effect of Remimazolam on Intraoperative Motor Evoked Potential Monitoring - Comparison with Propofol
Basic Information
| Recruitment status | Pending |
|---|---|
| Health condition(s) or Problem(s) studied | Spine Surgery Patients |
| Date of first enrollment | 2023/01/04 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Is there a difference in the amplitude and latency of MEP and SEP in the nerve travel area unrelated to the surgical site between general anesthesia with propofol and general anesthesia with remimazolam? Compare the difference between control and final MEP values in each case. |
|---|---|
| Secondary Outcome | Is there a difference between propofol and remimazolam in the time required from the end of anesthetic administration until neurologic findings can be obtained? |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | (1) Patients with epileptic seizures or history of epilepsy 2) Patients with muscle disease 3) Patients with peripheral neuropathy (iv) Patients in shock (5) Patients in coma (vi) Patients with a history of drug dependence (g) Patients with hepatic dysfunction |
Related Information
| Primary Sponsor | University of Occupational and Environmental Health, Japan |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | University of Occupational and Environmental Health, Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kotaro Hamada |
| Address | 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu City Japan 807-8555 |
| Telephone | 0936031611 |
| k-hamada@med.uoeh-u.ac.jp | |
| Affiliation | University of Occupational and Environmental Health, Japan Department of Anesthesiology |
| scientific contact | |
| Name | Kotaro Hamada |
| Address | 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu City Japan |
| Telephone | 0936031611 |
| k-hamada@med.uoeh-u.ac.jp | |
| Affiliation | University of Occupational and Environmental Health, Japan Department of Anesthesiology |