Wheat Bran Retention Enema as Adjuvant Therapy in children with Lower Respiratory Tract Infection

UMIN ID: UMIN000047319

Registered date:01/04/2022

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: Lower respiratory tract infection
• Date of first enrollment: 2022/04/15
• Target sample size: 40
• Countries of recruitment: Africa
• Study type: Interventional

Intervention(s)

The first group includes 18 patients who will receive conventional treatment and wheat bran enema.
The second group includes 21 patients who will receive conventional treatment only.

Outcome(s)

• Primary Outcome: In this work, we aimed to assess microparticle profiles, inflammatory and anti-inflammatory cytokine profiles in pediatric patients with CAP. Also, we aimed to assess the effect of the use of wheat bran retention enema on microparticle profile and inflammatory and anti-inflammatory cytokine profile in CAP to investigate the role of wheat bran as adjuvant therapy in the management of pediatric patients with CAP.
• Secondary Outcome: To the best of our knowledge, there is no current research addressing the role of wheat bran enema as adjuvant therapy in pediatric patients with CAP. In order to investigate the effect of wheat bran enema, we analyzed clinical, imaging and laboratory data regarding inflammatory and anti-inflammatory cytokine profiles in patients with CAP.

Key inclusion & exclusion criteria

• Age minimum: 1months-old
• Age maximum: 6years-old
• Gender: Male and Female
• Exclude criteria: Patients age less than one month and more than six years

Related Information

• Primary Sponsor: Assiut university Asyut Egypt
• Source(s) of Monetary Support: Assiut university Asyut Egypt