NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000045462

Registered date:15/09/2021

Predicting Deterioration of COVID-19 using Biomarkers

Basic Information

Recruitment status Pending
Health condition(s) or Problem(s) studiedCOVID-19
Date of first enrollment2021/09/20
Target sample size70
Countries of recruitmentJapan
Study typeObservational
Intervention(s)

Outcome(s)

Primary OutcomeNewly initiated oxygen therapy by 14 days after admission
Secondary OutcomeNational Institute of Allergy and Infectious Diseases (NIAID) ordinal scale and Japanese Ministry of Health, Labor, and Welfare severity classification of COVID-19 on Day 0,2,4,6,8,10,12,14, as well as on the day when oxygen therapy is initiated and the day when mechanical ventilation is initiated. In-hospital, 28-day, and 90-day mortality. Hospital-, ICU-, oxygen-, ventilator-, RRT-, and vasopressor-free days until Day 28 after admission. Tracheostomy and time when tracheostomy is performed. Organ failure score such as Sequential Organ Failure Assessment score (SOFA score) and Japanese Association for Acute Medicine disseminated intravascular coagulation criteria (JAAM DIC diagnostic criteria) on Day 0, 2, 7, 14 after admission.

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1) hepatitis C 2) Rheumatoid arthritis and autoimmune diseases 3) Immunosuppressed patients 4) Patient who is expected to die within 48 hours after admission 5) Patient who is considered to be inappropriate for the inclusion to this study by a treating physician

Related Information

Contact

public contact
Name Daiki Kaito
Address 35, Shinano-machi, Shinjuku-ku, Tokyo Japan 1608582
Telephone 0332251323
E-mail hoobar55@keio.jp
Affiliation School of Medicine, Keio University Department of Emergency and Critical Care Medicine
scientific contact
Name Koichiro Homma
Address 35, Shinano-machi, Shinjuku-ku, Tokyo Japan
Telephone 0332251323
E-mail homma@keio.jp
Affiliation School of Medicine, Keio University Department of Emergency and Critical Care Medicine