NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000042738

Registered date:01/03/2021

Immunogenicity and safety of the simultaneous administration of MR and yellow fever vaccines among Japanese adults

Basic Information

Recruitment status Pending
Health condition(s) or Problem(s) studiedYellow fever, Measles and Rubella
Date of first enrollment2021/06/01
Target sample size20
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Simultaneous administration of MR and yellow fever vaccines

Outcome(s)

Primary OutcomeImmunogenicity 1)Seroprotection to yellow fever after the simultaneous administration with yelloe fever and MR vaccines
Secondary OutcomeSafety 1)Adverse events wihin 28 days after the simultaneous administration with yelloe fever and MR vaccines Immunogenicity 2)Geometric mean titer(GMT) of yellow fever virus titer 4-6 weeks after the simultaneous administration with yelloe fever and MR vaccine 3)Seroconversion and GMTs of measles or rubella virus titers 4-6 weeks after the simultaneous administration with yelloe fever and MR vaccines

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum60years-old
GenderMale and Female
Include criteria
Exclude criteria1)Manifest fever (37.5 or more temperature) 2)Suffering from severe acute illness 3)History of anaphylaxis 4)Immunodeficiency 5)HIV infection 6)Immunosuppressive and Immunomodulatory Therapies 7)Neurological disorder 8)Thymus Disorder 9)History of hypersensitivity to MR and yellow fever vaccine 10)Other chronic medical conditions 11)Pregnancy 12)Brestfeeding 13)Other inappropriate condition for vaccination

Related Information

Contact

public contact
Name SHINJI FUKUSHIMA
Address 6-7-1 Nishishinjuku Shinjuku, Tokyo Japan 160-0023
Telephone 0333426111
E-mail fuku789@tokyo-med.ac.jp
Affiliation Tokyo Medical University Hospital Travellers' Medical Center
scientific contact
Name SHINJI FUKUSHIMA
Address 6-7-1 Nishishinjuku Shinjuku, Tokyo Japan
Telephone 0333426111
E-mail fuku789@tokyo-med.ac.jp
Affiliation Tokyo Medical University Hospital Travellers' Medical Center