Whole-body organ uptake of PET tracer [18F]SMBT-1

UMIN ID: UMIN000041176

Registered date:19/08/2020

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: healthy volunteer
• Date of first enrollment: 2020/08/20
• Target sample size: 8
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): injection of [18F]SMBT-1

Outcome(s)

• Primary Outcome: Standardized Uptake Ratio (SUV) after injection of [18F]SMBT-1 in each organ
• Secondary Outcome: Standardized Uptake Ratio (SUV) after injection of [18F]SMBT-1 in each organ and its time course information, as well as an estimated value of radiation exposure in each organ

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 70years-old
• Gender: Male and Female
• Exclude criteria: AN group (1) Pregnancy and breast feeding, and within 28 days after delivery (2) Severe allergic reactions to drugs and foods (3) Habitual smoking (including those who have smoked within 1 year) (4) Taboo conditions for MRI examinations (cardiac pacemaker, intracorpoporial metals, etc. to be checked with questionnaire in advance) (5) Sever deformity or deficienty of organs due to accidents, operations, and developmental problems. (6) Systemic circulatory and metabolic disorders as well as organ dysfuctions, such as diabetes melitus, hypertension, endocrinological disorders, congestive heart failure, angina petoris, severe renal dysfunctions (7) Being diagnosed or treated for malignant diseases within 1 year (8) Any sociomedial conditions, which may make the participation to this study difficult

Related Information

• Primary Sponsor: Tohoku University Cyclotron and Radioisotope Center
• Source(s) of Monetary Support: JSPS