NIPH Clinical Trials Search

UMIN ID: UMIN000038443

Registered date:06/11/2019

Examination of the wrinkle improvement effect in the consecutive use of the antiwrinkle product(MAW-1).

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedwrincle
Date of first enrollment2019/11/07
Target sample size30
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Apply quasi drug(MAW-1) 2 times a day for 12 weeks to the outer corner of a half face allocated randomly by assignment director. Apply placebo cosmetic 2 times a day for 12 weeks to the outer corner of a half face allocated randomly by assignment director.


Primary OutcomeThe wrincle depth evaluated by replica of eye area. Wrinkle grade judgment by the Dermatologist.
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum40years-old
Age maximum60years-old
GenderMale and Female
Include criteria
Exclude criteria1)Person with chronic skin symptoms such as atopic dermatitis, contact-related dermatitis, skin hypersensitivity 2)Person with the abnormality that is remarkable in the skin state of the face which is a test part 3)The person who receives hormone replacement therapy 4)Person with the experience of beauty medical care affecting the test part 5)The person who I receive special facial care (facial beauty treatment salon P ring laser), and does not pass more than one month 6)The person who takes in the supplement which declared diet or a fair skin effect routinely 7)The extreme person that I tan or work and sports are not avoided outdoors for a long time 8)The person who used pharmaceutical products, an unregulated drug, a supplement, the health food which might have an influence on the final examination regularly 9)Person with a history of the past when I am dangerously ill to heart, liver, a digestive organ 10)An excessive cigarette and an alcohol habitual offender and the person that the eating habits are extremely irregular 11)During the pregnancy or the person who plans the pregnancy all over the person, the study time nursing it 12)In addition, the person who judged that a study person in charge or the study person in charge was ill-qualified

Related Information


public contact
Name Hiromu Katsuta
Address 1-47-1, Higashiikebukuro , Toshima Ku, Tokyo To Japan 170-0013
Telephone 03-5928-2501
Affiliation ReLife,inc Clinical Trial Division
scientific contact
Name Taeko Chinen
Address 4-6-2, Nishisugamo, Toshima Ku, Tokyo To Japan
Telephone 03-3910-1136
Affiliation Medical corporation association Shizuyakai oozoranaika/hifuka Dermatology