Effect of exercise therapy combined with hyperthermia on blood BDNF concentration in healthy young men

UMIN ID: UMIN000037781

Registered date:23/08/2019

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: young healthy men
• Date of first enrollment: 2019/09/16
• Target sample size: 10
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Bicycle ergometer (60% of maximal oxygen uptake) 15 minutes in subjugated water at 40'C
40'C, subjugated water 15 minutes

Outcome(s)

• Primary Outcome: Serum and plasma brain-derived neurotrophic factor (BDNF; brain-derived neurotrophic factor) immediately after 15 minutes of warm bath exercise therapy
• Secondary Outcome: Plasma cortisol, lactic acid, Serum S 100 .BETA., neuron-specific enolase (NSE; neuron-specificenolase), Irisin, P selectin (CD 62 P), CBC (CBC; complete blood count), central temperature (esophageal temperature), blood pressure, heart rate, perceived exertion (Borg Scale), water temperature

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 39years-old
• Gender: Male
• Exclude criteria: Persons with diabetes mellitus, heart disease, chronic inflammatory disease, or skin disease.

Related Information

• Primary Sponsor: Wakayama Medical University
• Source(s) of Monetary Support: Wakayama Medical University