Elucidation of effects of chronic exercise on novel peptide hormones to prevent sarcopenia and chronic diseases

UMIN ID: UMIN000035520

Registered date:11/01/2019

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Young and Middle-aged and older adults including of obese adults
• Date of first enrollment: 2018/01/11
• Target sample size: 300
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Young subjects undertook a chronic aerobic exercise using cycle ergometer. The aerobic exercise-training program consisted of cycling on a leg ergometer for 45-55 min, 60-70% of maximal oxygen uptake, 3 days/week, for 8-12 weeks.
Middle-aged and older subjects undertook a chronic aerobic exercise using cycle ergometer. The aerobic exercise-training program consisted of cycling on a leg ergometer for 45-55 min, 60-70% of maximal oxygen uptake, 3 days/week, for 8-12 weeks.
Young subjects undertook a chronic resistance exercise. The resistance exercise-training program to whole body consisted for 10 repetitions, 3 sets, 60-70% of repetition maximum, 3 days/week, for 8-12 weeks.
Middle-aged and older subjects undertook a chronic resistance exercise. The resistance exercise-training program to whole body consisted for 10 repetitions, 3 sets, 60-70% of repetition maximum, 3 days/week, for 8-12 weeks.
Non intervention(Young subjects)
Non intervention(Middle-aged and older subjects)

Outcome(s)

• Primary Outcome: Effects of chronic exercise on circulating peptide hormone levels

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 80years-old
• Gender: Male and Female
• Exclude criteria: 1)Patients with hepatic dysfunction and/or renal dysfunction 2)Patients with cardiovascular diseases 3)Pregnant or plans to become pregnant during the study period 4)Patients with limited exercise therapy 5)Others who judged inappropriate by the examining physician

Related Information

• Primary Sponsor: Ritsumeikan University
• Source(s) of Monetary Support: Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan