NIPH Clinical Trials Search

UMIN ID: UMIN000034468

Registered date:01/11/2018

Effect of pregabalin on neuropathic pain in Yusho patients: open label pilot study

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedYusho
Date of first enrollment2018/12/01
Target sample size20
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)For the symptoms of numbness and sensation deterioration in Yusho patients, pregabalin 25 mg is orally administered for 4 weeks and the effect judgment is carried out and the result is analyzed. In addition, pregabalin should be administered in 4 weeks.


Primary OutcomeThe effect of pregabalin on sensory disorders such as numbness of the subjects is compared for each of VAS, Von frey, and heat sensation for each difference before pregabalin administration and at the end of administration (4th week after administration start).
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum50years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteriaPatients applicable to even one of the following are excluded as subjects. 1.Patient currently taking pregabalin 2.Patients with serious liver and kidney dysfunction 3.Patients with drug hypersensitivity such as allergy to pregabalin 4.In addition, patients whose research managers judged inappropriate as research subjects

Related Information


public contact
Name Yoshiyuki Kamio
Address 7-1 Sakamoto, Nagasakishi Japan 852-8501
Telephone 095-819-7333
Affiliation Nagasaki University Hospital Dermatology / Allergy Department
scientific contact
Name Hiroyuki Murota
Address 7-1 Sakamoto, Nagasakishi Japan
Telephone 0958197333
Affiliation Nagasaki University Hospital Dermatology / Allergy Department