Whether hybrid training during dialysis improve patient's physical function and inflammation and arteriosclerosis

UMIN ID: UMIN000033833

Registered date:29/08/2018

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: hemodyalysis people
• Date of first enrollment: 2016/04/01
• Target sample size: 40
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare with the placebo group.
We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare it with the exercise group.
We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare with the hybrid exercise group.

Outcome(s)

• Primary Outcome: Exercise tolerance test
• Secondary Outcome: Before exercise and after 3 months Grip strength time up Go test Lower limb muscle strength functional reach test Body composition measurement Thigh muscle area by MRI etc

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 90years-old
• Gender: Male and Female
• Exclude criteria: 1.Patients under the age of 20 years old 2.Patients who are contraindicated in the package insert of Levocarnitine 3.Patients undergoing combination therapy with peritoneal dialysis and hemodialysis 4.Pregnant woman, or a woman who have possibility of pregnancy 5.Others not inadequate judged by a physician 6.Patients who do not obtain consent

Related Information

• Primary Sponsor: Division of Nephrology, Department on Medicine, Kurume University
• Source(s) of Monetary Support: Division of Nephrology, Department on Medicine, Kurume University