NIPH Clinical Trials Search

UMIN ID: UMIN000031605

Registered date:20/04/2018

Study of longitudinal observation for patient with X-linked hypophosphatemic rickets/osteomalacia in collaboration with Asian partners

Basic Information

Recruitment status Complete: follow-up continuing
Health condition(s) or Problem(s) studiedX-linked hypophosphatemic rickets/osteomalacia
Date of first enrollment2018/05/01
Target sample size240
Countries of recruitmentJapan,Asia(except Japan)
Study typeObservational


Primary OutcomePatients aged,<18years:Height,Rickets Severity Score,QOL,and motor function Patients aged >=18years:QOL and motor function
Secondary OutcomePatients aged <18 years:Growth velocity, lower limb deformity,biomarkers for phosphorus metabolism and bone metabolism,and fracture Patients aged >=18 years:Biomarkers for phosphorus metabolism and bone metabolism,fracture,spinal ligament ossification,nephrocalcinosis,and renal function

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1. Participation in any clinical study (trial) sponsored by Kyowa Kirin at the time of informed consent 2. Any patient whose participation in the study is considered inappropriate by the investigator or the subinvestigator

Related Information


public contact
Name Etsuou Imai
Address 3-4-8 Hatchobori, Chuo-ku, Tokyo 104-0032, Japan Japan 104-0032
Telephone 03-5543-0302
Affiliation SRD Co., Ltd. Clinical Research Department
scientific contact
Name Keiichi Ozono
Address 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan Japan
Telephone 06-6879-5111
Affiliation Osaka University Graduate School of Medicine Pediatrics