When and how to remove prophylactic abdominal drains after elective liver resection: a retrospective observational study evaluating drain removal on the third and first postoperative day

UMIN ID: UMIN000030518

Registered date:22/12/2017

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Patients who underwent open liver resection at the University of Tokyo Hospital
• Date of first enrollment: 2017/11/24
• Target sample size: 80
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: The length of postoperative hospital stay
• Secondary Outcome: Incidences of major complications such as drain infection, bile leakage, and percutaneous puncture for fluid collection. The proportion of patients with complications classified as grade III or above according to the Clavien-Dindo classification was also evaluated.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 80years-old
• Gender: Male and Female
• Exclude criteria: Patients with any of the following were excluded: a need for bilioenteric reconstruction; required resection of another organ (except cholecystectomy); other malignant disease outside the liver; an indocyanine green retention rate at 15 minutes 20% or more; and severe co-morbidity, such as renal dysfunction (estimated glomerular filtration rate of 20 mL per min per 1.73 m2 or less), cardiovascular disease (necessitating intervention or an ejection fraction of no more than 50 percent), or a respiratory disorder (vital capacity below 60 percent or forced expiratory volume in 1 s of less than 50 percent).

Related Information

• Primary Sponsor: Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo
• Source(s) of Monetary Support: This study was self-funded and not sponsored.