Analyses of intravitreal antioxidant potential and cytokine profiles of various vitreoretinal diseases

UMIN ID: UMIN000022734

Registered date:01/12/2016

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: vitreoretinal diseases
• Date of first enrollment: 2015/05/01
• Target sample size: 200
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Collection of 0.5ml of undiluted vitreous fluid before starting vitrectomy for rhegmatogenous retinal detachment.
Collection of 0.5ml of undiluted vitreous fluid before starting vitrectomy for macular hole.
Collection of 0.5ml of undiluted vitreous fluid before starting vitrectomy for epiretinal membrane.
Collection of 0.5ml of undiluted vitreous fluid before starting vitrectomy for proliferative diabetic retinopathy.
Collection of 0.5ml of undiluted vitreous fluid before starting vitrectomy for retinal vein occlusion.

Outcome(s)

• Primary Outcome: Differences in the antioxidant potentials and cytokine profiles between various vitreoretinal diseases
• Secondary Outcome: Characteristic patterns of the antioxidant potentials and cytokine profiles in each of various vitreoretinal diseases

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 90years-old
• Gender: Male and Female
• Exclude criteria: Patients who were previously undergone vitrectomy surgery.

Related Information

• Primary Sponsor: Department of Ophthalmology, Hirosaki University Graduate School of Medicine
• Source(s) of Monetary Support: self-funding