Verifying the early diagnostic method of adenovirus-induced hemorrhagic cystitis after allogeneic hematopoietic stem cells transplantation

UMIN ID: UMIN000021015

Registered date:14/02/2016

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: adenovirus-induced hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation
• Date of first enrollment: 2016/02/15
• Target sample size: 20
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): Urinary adenoviral DNA is quantified in accordance with the schedule below. 1. Before the start of conditioning chemotherapy 2. Every two weeks after allogeneic hematopoietic stem cell transplantation 3. In case hemorrhagic cystitis has been developed, every week until improvement 4. At the outpatient clinic, once a month until one year post HSCT

Outcome(s)

• Primary Outcome: The efficacy of quantifying urinary adenoviral DNA for diagnosis of adenovirus-induced hemorrhagic cystitis

Key inclusion & exclusion criteria

• Age minimum: 16years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1. Patients whom hemorrhagic cystitis has already developed 2. Patients who are recognized as inadaptable for this trial

Related Information

• Primary Sponsor: Department of Hematology, Kanazawa University Hospital
• Source(s) of Monetary Support: Department of Hematology, Kanazawa University Hospital