NIPH Clinical Trials Search

UMIN ID: UMIN000017813

Registered date:04/06/2015

Evaluation test of wrincle improvement effect by application of eggshell membrane cosmetics (Super Odi Grand Evolution) (pilot study)

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedwrincle
Date of first enrollment2015/06/04
Target sample size21
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Apply 3 drops of Super Ode Grand Evolution containing hydrolyzed eggshell membrane 3 times a day for 2 weeks to the outer corner of a half face allocated randomly by assignment director. Three drops of placebo cosmetic that removed the hydrolyzed eggshell membrane from Super Ode Grand Evolution on the outer corner of the half face randomly assigned by assignment director were applied three times a day for 2 weeks.


Primary OutcomeThe wrincle depth evaluated by replica of eye area
Secondary OutcomeThe wrincle grade evaluated by a picture of eye area

Key inclusion & exclusion criteria

Age minimum30years-old
Age maximum60years-old
Include criteria
Exclude criteria(1) Person who has a history of allergy (2) Those receiving hormone replacement therapy (3) During pregnancy, breast-feeding (4) Persons who have experienced cosmetic care that will affect the site to be examined (5) A patch test was conducted on the test cosmetics and the replica agent, and a person with abnormality appeared on the skin (6) Person who is receiving facial beauty treatment (7) Others who acknowledge that doctors involved in the examination are not appropriate

Related Information


public contact
Name Miho Shimizu
Address 2-24-16 Nakacho, Koganei, Tokyo Japan
Telephone 042-388-7539
Affiliation Tokyo University of Agriculture and Technology Grad Sch of Eng, Dept of Appl Chem
scientific contact
Name Toshiyuki Watanbe
Address 2-24-16 Nakacho, Koganei, Tokyo Japan
Telephone 042-388-7289
Affiliation Tokyo University of Agriculture and Technology Graduate School of Engineering, Department of Applied Chemistry