The Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: a double-blind randomized trial

UMIN ID: UMIN000016585

Registered date:01/03/2015

Basic Information

• Recruitment status: Recruiting
• Date of first enrollment: 2015/03/01
• Target sample size: 80
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Platelet rich plasma
Platelet poor plasma

Outcome(s)

• Primary Outcome: Japanese Knee Osteoarthritis Measure(JKOM)
• Secondary Outcome: The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) Visualized Analog Scare(VAS) Knee Injury and Osteoarthritis Outcome Score (KOOS) Adverse event

Key inclusion & exclusion criteria

• Age minimum: 40years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: systemic or inflammatory joint diseases, haematological diseases, infections, Cancer/malignant lesions, surgical treatment within 6 months of inclusion, intra-articular pharmacological trtreatment within 3 months of inclusion, pregnancy, alcohol/drug abuse, Difficulties in comprehension and/or reading and writing, Physical impediments to answer questionnaire, poor general health as judged by the orthopaedic surgeon

Related Information

• Primary Sponsor: Department of orthopaedics, Juntendo university
• Source(s) of Monetary Support: Department of orthopaedics, Juntendo university