TNFa as predictor of early postoperative knee function and pain in fast-track total knee arthroplasty patients.

UMIN ID: UMIN000012646

Registered date:21/12/2013

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Osteoarthriris
• Date of first enrollment: 2013/12/21
• Target sample size: 50
• Countries of recruitment: Europe
• Study type: Interventional,observational
• Intervention(s): Elisa test. Questionnaires assessing level of preoperational anxiety were administered during interviews and were completed the same day by all patients.

Outcome(s)

• Primary Outcome: The primary outcome is ELISA test used to determine the levels of cartilage oligomeric matrix protein (COMP) and tumor necrosis factor-alpha.
• Secondary Outcome: The secondary outcome is anxiety assessed with the Spielberger State-Trait Anxiety Inventory state (STAI-S) and trait (STAI-T) scores.

Key inclusion & exclusion criteria

• Age minimum: 18years-old
• Age maximum: 80years-old
• Gender: Male and Female
• Exclude criteria: The exclusion criteria are lack of cooperation capability, revision surgery for TKA, rheumatoid arthritis, systemic or metabolic disorders, neurologic or psychiatric disease, alcohol abuse, patients younger than 18 and older than 80 years.

Related Information

• Primary Sponsor: Zietek
• Source(s) of Monetary Support: Own